What is the mechanism of action of Tapentadol Tablets?
Tapentadol 100 mg Tablets
Tapentadol is a potent opioid analgesic that belongs to the benzenoid class. It acts as both a norepinephrine reuptake inhibitor (NRI) and an agonist of the opioid receptor. Tapentadol, marketed under the brand name Nucynta, was approved by the US FDA in 2008, the MHRA of the UK in 2011, and the TGA of Australia in 2010. It provides relief from pain within 30 minutes of oral administration and its effects last for four to six hours.
How does Tapentadol work?
Tapentadol 100mg is a powerful painkiller that binds to opioid receptors in the spinal cord and brain. By regulating the levels of noradrenaline in the nervous system, it reduces the perception and response to pain. Tapentadol is used to treat both chronic and acute musculoskeletal pain, including diabetic neuropathy pain that requires opioid medication for 24-hour relief.
How to take Tapentadol?
When taking Tapentadol 100mg tablets, it is important to follow the instructions provided by your physician. Here are some key points to keep in mind:
- Read the manufacturer’s information leaflet before starting treatment to familiarize yourself with Tapentadol and its potential side effects.
- Take the tablet exactly as directed by your physician. The dosage instructions can be found on the label of the pack. For short-term pain relief, the typical dose is 50mg every four to six hours. You may be prescribed oral liquid medicine or standard tablets. If you require long-lasting pain relief, your physician may prescribe Palexia SR tablets, which release the drug slowly for a stronger painkilling effect. These tablets should be taken twice a day.
- Swallow the tablet with a glass of water after a meal. Do not crush or chew the tablet.
- Take note of the strength of the tablets and always verify it from the label when purchasing. If you have any doubts, consult your pharmacist for clarification.
- If you miss a dose, take it as soon as you remember. However, do not take two doses together.
Why use Tapentadol?
Tapentadol is an affordable medication that effectively relieves moderate to severe short-term pain, making it a preferred choice over other alternatives.
Common side effects
The most common side effects of Tapentadol include dizziness, sleepiness, vomiting, nausea, and constipation. In rare cases, serious side effects such as swelling/itching of the throat/face/tongue, rash, and difficulty breathing may occur.
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