Medications to Avoid Combining with Alcohol - The Right Way to Take Meds

Medications to Avoid Combining with Alcohol – The Right Way to Take Meds

Posted On July 26, 2023 at 5:13 pm by / No Comments

Potential Dangers of Mixing Alcohol with Medications

Many people wonder whether it is safe to consume alcohol while taking certain medications. This question is particularly important in the United States, where a significant portion of the population regularly takes prescription drugs. However, combining alcohol with medications can pose serious risks that outweigh any potential benefits. While moderate alcohol consumption may have some heart health benefits, the interactions between alcohol and medications can lead to various negative effects.

When alcohol is mixed with certain medications, the following interactions may occur:

  • Increased intoxication when alcohol is consumed alongside certain medications
  • New symptoms or increased illness due to the interaction between alcohol and medication
  • Worsening of the severe side effects associated with the medication
  • Toxicity in the body when alcohol is combined with certain medications
  • Reduced effectiveness of the medication due to the presence of alcohol

It is important for females to exercise extra caution when consuming alcohol and medications, as they tend to have higher blood alcohol levels than men even when consuming the same amount. This is because women have lower levels of the enzyme alcohol dehydrogenase, which helps break down alcohol in the body.

Older individuals should also be particularly careful when mixing alcohol with medications. As people age, it takes longer for their bodies to metabolize alcohol. This can result in higher alcohol levels in the blood, especially when combined with the use of medications. Therefore, older individuals have an increased risk of experiencing negative interactions between alcohol and medications.

Medications That Should Not Be Mixed with Alcohol


Consuming alcohol while taking painkillers such as naproxen (Naprosyn, Aleve), ibuprofen (Motrin), or acetaminophen can lead to stomach issues, ulcers, or even stomach bleeding. Additionally, mixing alcohol with opioids like oxycodone or codeine can result in slowed breathing, excessive drowsiness, and potentially even death.

Anti-Anxiety and Sleeping Tablets

Combining alcohol with sleeping pills or anti-anxiety medications can cause severe complications, including extreme fatigue or loss of consciousness.


Mixing alcohol with anti-depressant medications can lead to various symptoms such as dizziness, drowsiness, liver damage, movement problems, overdosing, and severe heart problems. Certain mood stabilizers like Divalproex and lithium can also have serious side effects when combined with alcohol.

ADHD Medicines

ADHD medications like Ritalin, Adderall, and Vyvanse can interact negatively with alcohol, resulting in liver damage, heart problems, poor concentration, drowsiness, and dizziness.


Drinking alcohol while taking antibiotics like metronidazole, nitrofurantoin, azithromycin, or isoniazid can cause unpleasant effects such as violent vomiting, nausea, or discomfort.

Nitrates and Other Blood Pressure Medicines

Combining alcohol with certain blood pressure medications or anti-angina drugs can lead to drowsiness, fainting, a faster heartbeat or arrhythmias, and dizziness.

Diabetes Drugs

Consuming alcohol while taking diabetes medications like insulin, metformin, glyburide, or glipizide can result in sudden changes in blood pressure, rapid heartbeat, headache, nausea and vomiting, flushing, and low blood sugar levels.


Combining warfarin with alcohol can have unpredictable effects on the body. Close monitoring is necessary to ensure that the blood does not become too thin.

Over-The-Counter Cold and Flu Medications

Many over-the-counter cold and flu medications contain a combination of painkillers, decongestants, antihistamines, and even alcohol. It is important to check the ingredients before consuming these medications with alcohol to avoid dizziness, drowsiness, and the risk of overdose.

Erectile Dysfunction Drugs

Consuming alcohol with erectile dysfunction medications like Viagra, Cialis, or Levitra can result in significantly lower blood pressure, leading to symptoms such as headache, dizziness, and flushing.


Mixing alcohol with medications, whether prescription or over-the-counter, can have unpredictable and potentially harmful effects. To protect oneself from these risks

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